Detailed description of pharamaceutical raw materials (dosage, indications)

Thetablebelow lists pharmaceutical raw materials to facilitate the selection of ingredients prescribed by a doctor in a specific disease. In addition, the tablealso contains suggested doses of individual ingredients taking into account the latest guidelines contained in the Polish Pharmacopoeia VIII, and the most frequently used and prescribed concentrations of the specific active substances in the compounded drug.

A description of pharmaceutical raw materials and dosage according to PP VIII.

Active substance `Action Contraindications Dose* [g] *(oral route, unless otherwise specified)
Normal use Maximum
Single 24 hours Single 24 hours
Acidum acetylsalicylicum NSAID, anti-fever, analgesic, anti-inflammatory, anti-aggregatory in small doses.

Indications: fever, flu, pain of various origin.

Allergy to salicylates 0,3 – 1,0 1,0 – 3,0 1,0 3.0 (acc. to PP IV up to 8.0)
Acidum ascorbicum Adjunctive treatment of cold. Renal insufficiency, nephrolithiasis 0,1 0,5
Acidum benzoicum Antibacterial, anti-rot, antiseptic, expectorant.

Indications: For rinsing the mouth and throat, preservative.

Hypersensitivity to benzoic acid Antibacterial rinsing solutions 0.1–1%

Sprinkles, ointments and pastes 2.0–10%

Acidum boricum Weak anti-inflammatory and antiseptic effects.

Indications: skin sores, for rinsing of wounds and mucous membranes, excessive feet sweating.

Not used internally because of neurotoxic effects and the possibility of accumulation in the body. Ointments and aqueous solutions at concentrations 1.0–3.0%,

Sprinkles up to 10%,

Intravaginal tablets up to 2% (acc. to PP VIII)

Acidum lacticum Anti-rot, bactericidal, astringent, cauterising, prebiotic properties.

Indications: for vaginal lavage in an inflammations, disinfecting, mouth ulcers, cauterisation, for peeling in cosmetic applications.

Do not use in sensitisation to lactic acid For rinsing 0.5–2.0% (for mucous membranes 0.5%)

For brushing 10.0–20.0%

For cauterising 20.0–50.0 (acc. to PP VIII)

Acidum salicylicum Antiseptic, analgesic, anti-inflammatory, keratolytic and keratoplastic, antifungal.

Indications: skin disinfection, removal of calluses and thickened skin, increased feet sweating.

Allergy to salicylates Antiseptic 1.0–3.0% (maximum single dose 10%)

Keratoplastic 10.0–20.0%, Keratolytic 20.0–50.0%

According to the latest regulations Keratolytic 10.0–20.0 % (PP VIII)

Acidum tannicum (Tanninum) Highly astringent, weak disinfecting action, haemostatic, reducing inflammation.

Indications: skin inflammation, excessive sweating, minor bleeding.

Hypersensitivity to tannin. Skin solutions 1.0–20.0%

Enemas 0.5%

Ointments 5.0–10.0%

Sprinkles up to 20.0%

Adonis vernalis tinctura Weak and short-term action that increases the contraction power of the cardiac muscle and slows it down.

Indications: mild heart-induced circulatory insufficiency, sedative.

Allergy to any of the ingredients of the tincture, pharmacotherapy with other preparations having the same cardiac function profile. 1,0 3,0 3,0 10,0
Alumini subaceticum solutum Astringent, anti-inflammatory.

Indications: bruises, oedema, inflammation.

Do not use on open wounds Mainly used for compresses at a dilution of 1:3–1:2
Ammonium bituminosulfonicum (Ichthyol) Mild disinfectant, irritant, anti-inflammatory and anti-oedema.

Indications: psoriasis, ulcerations, oedema, skin diseases, vaginal inflammation.

Allergy to Ichthyol, do not apply to damaged skin. Externally for rinsing 1.0–5.0%

On the skin 2.0–15.0%, ointments and liniments 10.0–15.0%

Suppositories and intravaginal tablets 1.0–5.0% (PP VIII)

Ammonium bromatum Strong sedative, facilitates falling asleep, high doses inhibit epilepsy seizures.

Indications: insomnia, neurosis, increased excitability.

Tuberculosis, inflammation of the digestive tract. Acc. to PP VIII, the maximum daily dose is 0.5 g of ammonium bromide.

For mixtures of bromides, a maximum of 1.0 g per day, including 0.5 g of ammonium bromide.

Ammonium chloratum Expectorant, secretolytic for the respiratory tract, acidifying for the organism (diuretic).

Indications: inflammation of the respiratory tract, alkalosis, circulatory insufficiency.

0,3 – 0,5 1,0 – 1,5 1,0 6,0
Argentum colloidale Bactericidal

Indications: inflammation of mucous membranes.

Solutions 0.2–1.0%

Ointments 1.0–15.0%

Argentum nitricum Bactericidal, cauterising, disinfecting, astringent.

Indications: purulent inflammation of mucous membranes, in dentistry for impregnation of deciduous teeth in decay processes, in high concentrations for the cauterisation of tissues.

On the skin 1.0–2.0%

For rinsing 0.05–0.1%

For oral brushing 1.0–2.0%

Dentistry 10.0–20.0%

Argentum proteinicum Bactericidal, anti-inflammatory. Unlike other salts, silver is not caustic.

Indications: purulent inflammation of mucous membranes.

On the skin and mucous membranes 0.25–2.0%

Eye drops 0.5–1.5%.

Balsamum peruvianum Anti-inflammatory, antiparasitic, for skin burns/frostbite as a compress.

Indications: difficult to heal wounds, ulcerations, scabies.

Externally at concentrations 5.0–10.0% (ointments)

Older sources also report the use at 5.0% in suppositories for haemorrhoids.

Belladonnae extractum siccum Parasympatholytic, reduces glandular secretion.

Indications: for use in gastroenterology, as adjunctive treatment of peptic ulcers, gastrointestinal contractions, constipation.

Paralytic ileus, pregnancy, prostate hypertrophy. 0,01 – 0,02 0,03 – 0,05 0,05 0,15
Belladonnae tinctura As for Belladonnae extractum siccum. As for Belladonnae extractum siccum.

 

0,1 – 0,5 0,3 – 1,5 1,0 3,0
Benzocainum (Anaesthesinum) Local anaesthetic,

Indications: painful ulcerations, wounds, itching, painful symptoms of stomach hyperacidity.

Hypersensitivity to benzocaine. 0,3 0,5 0,5 1,5
Sprinkles and ointments up to 10.0%

Suppositories and solutions 1.0–3.0%

Bismuthum subcarbonicum Protective and neutralising excess acid in the stomach, astringent.

Indications: externally for burns and wounds, orally for peptic ulcers, diarrhoea and ileus.

0,5 1,5 1,0 3,0
Sprinkles 3.0–10.0%

Ointments 5.0–20.0 %

Bismuthum subgallicum (Dermatol) Astringent, weak antiseptic, used externally as a drying and protective agent.

Indications: diarrhoea, ileus, ulcerations, exudating wounds, skin inflammation.

0,2 0,4 0,4 0,8
Sprinkles up to 25.0%

Ointments up to 20.0%

Bismuthum subnitricum Astringent, anti-inflammatory, drying, protective.

Indications: gastrointestinal ileus and ulcerations, diarrhoea, externally for skin ulcerations and wounds.

0.5–2.0 acc. to PP IV 6.0 acc. to PP IV
Sprinkles 10.0–20.0%

Ointments 5.0–20.0% (acc. to PP VIII)

Calcium carbonicum praecipitatum Neutralising gastric acid, anti-diarrhoea, anti-flatulence, supplementing calcium deficiencies. Externally astringent and drying.

Indications: hyperacidity, diarrhoea, osteoporosis.

Renal insufficiency, nephrolithiasis. 0,4 – 0,8 1,2
Calcium chloratum Antihemorrhagic, antipuritic, anti-exudative, calcium deficiency in the body.

Indications: haemorrhage, seasonal allergic rhinitis, potassium poisoning, tetany, allergic diseases.

Renal damage and renal insufficiency, nephrolithiasis, therapy with digitalis glycosides. i.v. 0,25 – 1,0

p.o. 0.2

i.v. –

p.o. —

i.v. 2,0

p.o. —

i.v. –

p.o. 0,6 – 1,0

Calcium gluconicum Calcium therapy As for Calcium chloratum 0.5–1.0 acc. to PP IV 3.0–6.0 acc. to PP IV 2.0 acc. to PP IV 10.0 acc. to PP IV
Calcium lacticum Calcium therapy As for Calcium chloratum 0.3–1.0 acc. to PP IV 3.0–5.0 acc. to PP IV 3.0 acc. to PP IV 8.0 acc. to PP IV
Camphora Topically irritant, warming, mild aesthetic.

Indications: muscle pain, joint pain, adjunctive treatment of acne vulgaris.

Allergy to camphor and derivatives. Ointments and liniments 1.0–10.0%

Solutions 0.1–1.0 %

Capsici tinctura Topically warming and irritating

Indications: rheumatic pain, joint pain, neuralgia.

Allergy to capsaicin. Externally for rubbing 1.0–15.0%
Chloralum hydratum Strongly soporific, sedative.

Indications: insomnia, hysteria.

Inflammation of the digestive tract, kidney diseases, heart diseases, prolonged use may cause damage to the liver. 1.0 acc. to PP IV 3.0 acc. to PP IV 2.0 acc. to PP IV 6.0 acc. to PP IV
Chloramphenicolum (Detreomycyna) Antibacterial, for external use.

Indications: purulent skin diseases, boils, purulent conjunctivitis.

Coexisting mycosis, allergic reactions, psoriasis, do not use in children or pregnant women. Ointments up to 2.0%

Eye ointments 1.0%

Eye drops 0.5%.

Chlorhexidini gluconas Disinfecting in rinses and solutions

Indications: mycosis of mucous membranes, for disinfecting skin and mucous membranes, for disinfecting laboratory surfaces.

Allergic reactions to chlorhexidine, for external use only. 0.02–0.05% solutions for mucous membranes

1.0% ointments, creams, gels

0.05–0.2% disinfectant solutions

1.0% solutions for disinfecting equipment

Codeinum phosphoricum Weaker analgesic than morphine, sedative, antitussive (cough suppressant).

Indications: acute dry cough, irritation of vocal chords, in sedative tinctures.

In children under 1 year of age, cough with purulent secretion, use of MAO inhibitors, constipation. 0,03 0,06 0,12 0,3
Coffeinum natrium benzoicum Stimulating the central nervous system, accelerates breathing, diuretic, expands skin blood vessels, weak effect on blood pressure.

Indications: cold, headache, fatigue, adjunctive treatment in circulatory failure or collapse.

Hypertension, angina pectoris, insomnia, neurosis 0,1 – 0,2 0,3 – 0,5 0,3 1,5
Collodium Protective for damaged tissues

Indications: skin sores, liquids for calluses

Convallariae maialis tinctura Strong cardiac effects, positive inotropic effect and negative chronotropic effect.

Indications: strengthening the heart functioning in elderly people, with neurotic heart disorders.

Do not use for treatment with digitalis glycosides, renal or hepatic damage, atherosclerosis. 0.5 acc. to PP IV 2.5 acc. to PP IV 1.5 acc. to PP IV 5.0 acc. to PP IV
Crataegi tinctura Hypotensive, positive inotropic effect, mildly sedative.

Indications: heart problems of psychogenic origin, hypertension.

1.0–1.5 acc. to PP IV 3.0–5.0 acc. to PP IV
Cuprum sulfuricum Irritating to the digestive system (emeticum), externally antifungal, bactericidal, astringent, caustic in higher concentrations.

Indications: mouth and skin mycosis, wound rinsing, copper deficiency

0,0005 0,0015
Emeticum: 0.25–0.3 in half a glass of water.

Externally 0.5–1.0%

Dithranolum Irritating to skin, keratolytic and keratoplastic, bactericidal, fungicidal.

Indications: mycosis, lichen, psoriasis.

Uczulenie na związki fenolowe, choroby nerek, stany zapalne skóry, niedokrwistość. 0.5–2.0% in the form of ointments or solutions.
Ephedrinum hydrochloricum Increases blood pressure, analeptic, increases the concentration of catecholamines, stimulates mentally, constricts vessels in the nasal mucosa, dilates pupils.

Indications: bronchial asthma, nocturnal enuresis, morphine and barbiturates poisoning, nasal mucosa inflammation.

Coronary disease, hypertension, hyperthyroidism. 0,025 0,05 – 0,1 0,05 0,15
For nose as droplets/ointments 0.5–2.0%
Erythromycinum A macrolide antibiotic with a bacteriostatic effect, also bactericidal at higher doses.

Indications: bacterial infections.

Hypersensitivity to macrolide antibiotics, severe liver damage. Individual dosing as required.

Externally as ointments 1.0–2.0%

Ethacridini lactas Disinfection of cuts; hard-to-heal, purulent wounds (compresses, wet compresses). Pregnant and lactating women. 0.01–0.2% antibacterial solutions

0.5–2.5% ointments, sprinkles

Formaldehydum 35% Strong disinfectant (causing tissue necrosis), anti-sweat, astringent.

Indications: excessive sweating, removing skin warts.

Pregnant and lactating women, causes severe respiratory irritation. Use only externally.

5.0–10.0% for skin sweating (spirit solutions)

2.0–10.0% solutions for disinfecting equipment and premises

Gentamycinum Antibiotic of the aminoglycosides group with anti-bacterial effect (bactericidal).

Indications: wound infections, conjunctivitis, acne vulgaris.

Allergy to antibiotics of the aminoglycosides group, renal damage, may cause auditory nerve damage. Ointments 0.1–0.3%

Eye ointments 0.3%

Solutions 0.3%

Glycerinum 85% Oral and rectal, laxative, helps remove kidney stones, solutions above 20% are antiseptic, softens the skin.

Indications: constipation, nephrolithiasis, chapped skin.

Orally, single dose 40.0 – 100.0

Enemas 10.0 – 20.0

Gummi arabicum Protective for the mucous membrane of the gastrointestinal tract.

Indications: protective during diarrhoea and poisoning, adjunctive when compounding the emulsion.

Hydrargyrum praecipitatum album Aseptic, antiparasitic, disinfecting, antifungal.

Indications: parasitic and fungal diseases of the skin.

Strongly toxic substance not for internal use. Ointments and sprinkles 2.0–10.0%
Hydrocortisoni acetas Anti-inflammatory, reduces oedema and skin itching, anti-allergic.

Indications: inflammations, eczema, allergic rashes, insect bites, in the treatment of haemorrhoids.

Pregnancy and nursing women, hydrocortisone is not recommended in newborns. Ointments (liniments) and suppositories up to 1.0%
Hydrogenium peroxydatum Bactericidal, dehydrating, bleaching.

Indications: wound disinfection, rinsing of the throat in inflammatory conditions, bleaching ointments in cosmetic applications.

Externally as solutions up to 3%

For oral rinsing 0.2–0.3%

Iodi puri Bactericidal, disinfecting.

Indications: for disinfecting mucous membranes and skin, in iodine therapy.

Allergy to iodine. 0,005 0,015 0,02 0,06
Externally as solutions 1.0–5.0%
Ipecacuanhae tinctura Expectorant, secretolytic, emetic at higher doses. (emetica)

Indications: in a productive cough during cold.

Heart diseases, ischemic disease, peptic ulcers. 0.3–0.5 acc. to PP IV 1.0 acc. to PP IV 1.0 acc. to PP IV 4.0 acc. to PP IV
Kalium bromatum Weak sedative, facilitates falling asleep, anti-epileptic at higher doses.

Indications: excessive nervous excitability, problems with falling asleep.

Gastrointestinal inflammation, renal insufficiency. Acc. to PP VIII, the maximum daily dose is 0.5 g of ammonium bromide.

For mixtures of bromides, a maximum of 1.0 g per day, including 0.5 g of ammonium bromide.

Kalium hypermanganicum Antibacterial, antiseptic.

Indications: for washing sores and wounds, rash, allergic reactions, in gynaecology for washing.

Externally in the form of mucosa and skin wash solutions 0.02–1.0%.
Kalium iodatum Increases bronchial mucus secretion (expectorans), inhibits atherosclerosis development, lowers blood pressure.

Indications: cold respiratory inflammation, atherosclerosis, hypothyroidism.

Allergy to iodine, tuberculosis, decrease in body weight. 0,05 – 0,5 0,15 – 3,0 2,0 6,0
Lidocainum hydrochloricum Local anaesthetic and antiarrhythmic.

Indications: local and infiltration anaesthesia.

Externally on skin and mucous membranes 1.0–4.0%
Magnesium oxydatum Neutralising, adsorbing, in small doses anti-diarrhoeal.

Indications: hyperacidity, peptic ulcers.

0,25 – 0,5 1,0 – 2,0
Magnesium sulfuricum Strong laxative, cholagogic.

Indications: constipation, cholelithiasis

10,0 – 20,0 10,0 – 20,0
Menthae piperitae tinctura Gas relief, relaxant for the gastrointestinal tract, antiemetic, improves digestive processes.

Indications: no appetite, indigestion, flatulence, vomiting.

Allergy to peppermint, do not administer to children up to 6 years of age due to irritating effects of menthol on the respiratory tract. 1,0 – 2,5
Mentholum Stimulates nerve endings causing a cool sensation, warming, weak local anaesthetic, antipuritic.

Indications: neuralgia, skin rash, inflammation of the mucous membranes of the throat.

Allergy to menthol, do not use in children under 6 years of age. Externally on mucous membranes up to 0.3%

On skin as ointments and solutions up to 10.0%.

Metamizolum natrium NSAID, strong analgesic and anti-fever effect, weak anti-inflammatory effect, relaxant.

Indications: classic anti-fever medicine, various pains of different origins, including postoperative, for short-term treatment.

Do not use for prolonged periods. Do not use in persons with renal insufficiency, blood disorders, hepatic insufficiency. p.o. 0.5–1.0

per rectum 0,75

p.o. 2,0

per rectum 1,5 – 3,0

p.o. 1,0

p.o. 3,0

per rectum 3,0

Metronidazol Antiprotozoal, antiparasitic, antibacterial.

Indications: trichomoniasis and similar infections (lamblia, demodex).

Pregnancy, purpura. p.o. 0,5

intravag. 0.5 0,5

per rectum 1,0

p.o. 1,0

intravag. 1.0 1,0

per rectum 1,0

p.o. –

intravag. 1.0 1,0

per rectum 1,0

p.o. 2,0

intravag. 1.5 1,5

per rectum 2,0

Morphinum hydrochloricum Strong analgesic, depressant to the nervous system and respiratory centre, eliminates peristalsis, causes constipation, narrows pupils, reduces diuresis.

Indications: severe pain, postoperative pain and palliative medicine.

Respiratory failure, bronchial asthma, liver lesions, opiate addiction. Individually determined by the doctor, causes strong addiction and habits.
Natrium benzoicum Expectorant, antiseptic, secretolytic, preservative.

Indications: upper respiratory tract inflammations.

Hypersensitivity to benzoic acid. 0,3 – 1,0 3,0
Natrium biboricum (tetraboricum) Antiseptic, astringent, fungicidal.

Indications: disinfecting mucous membranes, aphthae.

Renal insufficiency, damaged gastric and intestinal mucosa. Sprinkles, ointments, solutions 0.5 – 4%

For brushing, glycerine solutions 10.0 – 20.0%

Natrium bicarbonicum Neutralises the gastric juice, highly alkaline, increases secretion in the respiratory tract.

Indications: metabolic acidosis, inflammation of the mucous membranes.

Metabolic alkalosis, sodium retention. 0,15 1,5
Natrium bromatum Sedative, anti-convulsant, facilitates falling asleep.

Indications: excessive nervous excitability, convulsions, hyperthyroidism.

Allergy to bromine, renal insufficiency. 1.0 (including max. 0.5 ammonium bromide)
Natrium chloratum Electrolyte, maintains plasma and non-cellular fluids osmotic pressure.

Indications: NaCl deficiency, burns, vomiting, diarrhoea, hypotonic dehydration.

Sodium and water retention. Depending on the deficiencies 0.9% i.v., for the preparation of isoosmotic solutions.

Ointments and solutions up to 10.0%

Natrium salicylicum Analgesic, anti-fever, anti-inflammatory, antiseptic.

Indications: rheumatic diseases, upper respiratory tract inflammations, cold, flu, angina.

Hypersensitivity to salicylates, peptic ulcers, damaged gastrointestinal mucosa, liver and kidney damage. 0.5–1.0 acc. to PP IV 10.0 acc. to PP IV 2.0 acc. to PP IV 12.0 acc. to PP IV
acc. to PP VIII external antiseptic up to 1.0%
Neomycinum Aminoglycoside antibiotic, bacteriostatic and bactericidal, effective also against spirochaetes and protozoa.

Indications: bacterial diarrhoea, ophthalmology, bacterial skin infections and hard-to-heal wounds, burns.

Allergy to aminoglycoside antibiotics. Externally at concentrations 1.0–3.0%
Nystatinum Antifungal antibiotic, poorly absorbed from the gastrointestinal tract, low toxicity.

Indications: mycosis and candidiasis of the mouth and digestive tract, vagina and skin. Preventive in oral antibiotic therapy.

Allergy to nystatin. 500,000 IU 1.5 m IU p.o. 3.0 m IU

intravaginal 100,000 IU

Papaverinum hydrochloricum Reduces smooth muscle tone; increases coronary, cerebral, pulmonary flow; removes spastic conditions of bronchia, bile ducts, urinary tract.

Indications: spastic condition of smooth muscles.

Glaucoma. 0,04 – 0,1 0,3 0,2 0,6
Paraffinum liquidum Orally – laxative, protecting the intestinal mucosa.

Externally – moisturising, protective.

Indications: constipation, for compounded drugs.

15,0 30,0
Phenobarbitalum natricum (Luminalum natrium) Sedative, soporific, anti-epileptic at higher doses.

Indications: excessive nervous excitability, insomnia, at small doses reduces bilirubin levels in the blood.

Coronary disease, myasthenia, renal and hepatic impairment, pregnancy and nursing. 0,1 0,3 0,3 0,6
Pilocarpinum hydrochloricum Stimulates parasympathetic nerve endings, stimulates saliva secretion and perspiration.

Indications: glaucoma, atropine poisoning, for hair growth.

Pregnancy and nursing, bronchial asthma, spastic condition of smooth muscles. Eye drops in glaucoma 1.0–4.0%

To rub on skin 0.5%

Pix liquida Pini Disinfecting, anti-inflammatory, drying, reduces skin itching, antifungal, antiparasitic.

Indications: mycoses and skin infections, eczema, seborrhoea.

Renal disease, avoid sunlight when using Pix liquida Pini. Alcohol solutions 5.0–20.0%

Liniments and pulps 2.0–10.0%

Ointments 5.0–20.0%

Prednisolonum Anti-inflammatory, four times as strong as hydrocortisone, anti-allergenic.

Indications: inflammation and allergy.

Mycoses, tuberculosis, viral diseases.. Externally at concentrations 0.25–0.5%
Prodermin (Pix Lithantracis) Antiseptic, anti-inflammatory, drying, reduces skin itching, antifungal, antiparasitic.

Indications: bacterial and fungal skin infections, prurigo, seborrhoea, eczema.

Renal disease. Ointments, liniments, pastes, solutions 5.0–20.0%..
Resorcinum Keratolitic, anti-inflammatory, astringent, bactericidal, fungicidal.

Indications: psoriasis, acne, bacterial dermatitis, seborrhoea eczema, fungal infections.

Toxic compound. Do not use in patients with hepatic and renal insufficiency. Ointments and pastes 5.0–10.0%

Solutions 1.0–5.0%

Saccharum lactis Laxative.

Indications: constipation in infants and young children.

Allergy to lactose. Acc. to age 4.0–10.0.
Sapo kalinus Disinfecting, locally alkalising, softens the epidermis, antiseborrhoeic.

Indications: adjunctive treatment in scabies.

Topically several times a day, usually a component of complex ointments.
Sulfur praecipitatum Antifungal, antibacterial, anti-scabies, drying.

Indications: seborrhoea, acne, scabies, mycoses and excessive skin peeling.

Ointments, sprinkles, suspensions 5.0–10.0%
Talcum venetum Protective, drying, lubricant.

Indications: increased sweating, a base for sprinkles and powders.

Externally per se and in powders and sprinkles.
Tanninum Reduces inflammation, astringent, haemostatic.

Indications: skin inflammation, excessive sweating, minor bleeding.

Allergy to tannin and derivatives. Externally as solutions 1.0–20.0%

Ointments 0.5–10.0%

suppositories 0.05 suppositories 0.25
Thymolum Bactericidal, antipruritic, expectorant.

Indications: skin itch, oral cavity disease, adjunctive treatment in respiratory tract inflammations.

Allergy to thymol. Spirit solutions 0.5–3.0%

Ointments and oil solutions 1.0–2.0%

Mouth washes 0.05–0.1%

Urea Concentration-dependent action: moisturising (2%), softening (15%), keratolitic (above 30–40%)

Indications: skin diseases, allergies.

Externally from 2.0–30.0%
Valerianae tinctura Sedative, reduces excessive nervous excitability.

Indications: neuroses of different origin, insomnia.

Allergy to valerian. 1.0–3.0 acc. to PP IV 10.0 acc. to PP IV
Zincum oxydatum Astringent, drying, anti-inflammatory.

Indications: infected wounds, bed sores, acne, antiperspirant, sprinkles.

Externally in the form of ointments and pastes 15.0–25.0%